Parasite protection is a vital component of your cat's healthcare regimen. Whether your feline enjoys indoor naps or outdoor adventures, it’s essential to protect them from fleas, ticks, heartworms, and other harmful parasites.
With numerous options available, selecting the proper treatment can be overwhelming. In this guide, we’ll compare three popular cat parasite preventatives—Advantage Multi, Frontline Plus, and Revolution Plus—so you can decide which one offers the ideal protection for your pet.
Why Parasite Prevention Matters
Parasites such as fleas, ticks, heartworms, and intestinal worms can cause severe health issues in cats. Even indoor cats are not entirely safe. Fleas can easily make their way into your home by clinging to your clothing or shoes, and mosquitoes—known carriers of heartworm—can slip inside through even slightly open windows or doors.
Without proper prevention, your cat may suffer from:
- Itchy skin and allergic reactions
- Anemia from flea infestations
- Lyme disease and other tick-borne illnesses
- Deadly heartworm infections
- Intestinal issues due to roundworms or hookworms
Preventative treatment is not only safer than treating an existing infestation—it’s also more cost-effective and far less stressful for both you and your cat.
Product Comparison Overview
Let’s explore how Advantage Multi, Frontline Plus, and Revolution Plus stack up in terms of parasite protection, application, safety, and more.
1. Advantage Multi for Cats
Active Ingredients: Imidacloprid and Moxidectin
Targets: Fleas (adults), heartworms, roundworms, hookworms, ear mites
Application: Monthly topical treatment
Pros:
- Offers broad internal parasite coverage
- Prevents heartworm disease, which many flea treatments do not
- Kills adult fleas on contact—no need for them to bite
- Quick-drying and easy to apply
Cons:
- Does not protect against ticks
- Prescription-only medication
Best For: Cat parents who want all-in-one protection against fleas and internal parasites, especially heartworms.
2. Frontline Plus for Cats
Active Ingredients: Fipronil and (S)-methoprene
Targets: Fleas (adults, eggs, larvae), ticks, lice
Application: Monthly topical treatment
Pros:
- Provides excellent flea and tick protection
- Waterproof—ideal for cats that get wet or are bathed regularly
- Available over-the-counter
Cons:
- Does not prevent heartworm or intestinal worms
- Fleas must bite your cat to be affected
Best For: Owners seeking strong flea and tick protection without needing a vet prescription.
3. Revolution Plus for Cats
Active Ingredients: Selamectin and Sarolaner
Targets: Fleas, ticks, heartworms, ear mites, roundworms, hookworms
Application: Monthly topical treatment
Pros:
- Broadest spectrum of protection among the three
- Controls six types of parasites, including ticks and heartworms
- Starts working quickly—kills fleas within 6 hours
- Safe for kittens over 8 weeks old
Cons:
- Slightly more expensive than the other two options
Best for: Pet parents seeking comprehensive protection against both internal and external parasites.
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Application |
Topical |
Topical |
Topical |
Active Ingredients |
Selamectin and Sarolaner |
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Dosage |
Monthly |
Monthly |
Monthly |
Fleas |
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Eat Mites |
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Chewing Lice |
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American Dog Ticks |
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Brown Dog Ticks |
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Lone Star Ticks |
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Black-Legged Ticks |
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Gulf Coast Ticks |
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Prevent Heartworm |
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Roundworms |
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Hookworms |
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Which One Should You Choose?
- For broad-spectrum protection (including ticks and heartworms): Go with Revolution Plus.
- For a budget-friendly flea and tick solution: Choose Frontline Plus.
- For heartworm and internal parasite prevention without tick coverage: Pick Advantage Multi.
Always consult your vet before starting any parasite prevention treatment. Your vet can help you choose the best product based on your cat’s age, health status, and lifestyle.
Final Thoughts
Choosing the right parasite preventative isn’t just about convenience—it’s about protecting your cat’s long-term health. Whether you opt for Advantage Multi, Frontline Plus, or Revolution Plus, maintaining consistency with monthly treatments is crucial to preventing infestations and serious diseases.
If you’re looking for trusted and affordable parasite protection for your cat, explore our range at 79Pets.com. We offer competitive prices and ship directly to your doorstep.