Comparison: Nexgard vs. Frontline Plus For Flea And Tick Control


You probably know how crucial it is to protect your furry friend from ticks and fleas. But with many options, picking the right product to keep these pests away can be overwhelming.

Nexgard and Frontline Plus are well-known and efficient choices for keeping fleas and ticks at bay. Deciding between the two depends on what best suits you and your pet.

Topical Or Chewable?

Choosing between topical and chewable flea and tick control is a big decision. Frontline Plus for cats and dogs is a liquid you apply on their skin, while Nexgard is a chewable tablet your dog can eat. It is important to note that Nexgard is only for dogs; if you need flea and tick control for your cat, Frontline Plus is the way to go.

Each type has its perks. Topical treatments like Frontline Plus are great for cats and older or unwell dogs who might struggle with pills. Conversely, chewables like Nexgard are simple to give, leave no mess, and won't rub off easily, making them hassle-free for families with kids or multiple pets.

Killing Flea Eggs And Larvae

Eliminating flea eggs and larvae is crucial in controlling flea infestations. Frontline Plus targets flea eggs and larvae, while Nexgard focuses on killing newly hatched fleas before they can reproduce.

Frontline Plus gets rid of fleas within 12 hours and ticks within 48 hours after applying it. Nexgard, however, wipes out all fleas within 24 hours of administration.

Other advantages:

Frontline Plus and Nexgard are designed to tackle fleas and ticks each month. However, they have some slight variations.

Mosquitos and other parasites

Frontline Plus offers an extra perk by repelling mosquitoes and controlling biting lice. If you choose NexGard, you can pair it with Heartgard Plus to protect your pet against heartworms and intestinal worms.

You can use our comparison chart for the most popular flea and tick products.

Frontline Plus Cats & Dogs
Kills Fleas
Repels Fleas
Kills Flea Eggs and Larvae
Kills newly emerged fleas before they can lay eggs
Kills Ticks
Repels Ticks
Kills and/or Repels Mosquitoes
Other Parasites
Eliminates infestations with chewing lice, aids in the control of sarcoptic mange infestation
Safe for Pregnant or Nursing Pets
When does it starts working
Kills 100% of fleas within 24 hours
Kills fleas within 12 hours and ticks within 48 hours
Beef-flavored chewable
Active Ingredient(s)




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