Afoxolaner

Common brand names

Single Ingredient

Combined Ingredients

No generic products are available.

Use of Afoxolaner 

Afoxolaner is an ectoparasiticide that uses for the treatment of fleas and ticks. The ticks differ from region to region.

EU: castor bean ticks (Ixodes ricinus), brown dog ticks (Rhipicephalus sanguineus), and Marsh ticks (Dermacentorreticulatus).

USA: black-legged/deer ticks (Ixodes scapularis), American dog ticks (Dermacentorvariabilis), brown dog ticks (Rhipicephalus sanguineus), Lone star ticks (Amblyommaamericanum).

AUS: bush ticks (Haemaphysalislongicornis), Paralysis ticks (Ixodes holocyclus), brown dog ticks (Rhipicephalus sanguineus).

Method of application

Afoxolaner for dogs comes in flavored chew and needs to administer orally.

Dosage and administration

Afoxolaner is available in chewable form depending on the brand, for example, Nexgard. The recommended dosage and frequency of administration will depend on the product and the dog's weight. The dosage is based on the dog's weight, and it is important to use the correct dosage for the dog's weight. It is essential to follow the instructions on the product label and consult a veterinarian before administering the medication to your dog.

For example, Nexgard is available in four different strengths (based on the dog's weight) and is given once a month. The dosage is as follows:

It is important to note that these are just examples; dosage and administration may vary depending on the brand and product. Consult with a veterinarian for the best treatment for your dog.

Possible side effects

Afoxolaner, like all medications, can cause side effects in some dogs. The most common side effects are mild and temporary and may include the following:

  • Redness or itching at the site of the application
  • Diarrhea or vomiting
  • Loss of appetite
  • Lethargy or drowsiness

These side effects are usually mild and go away on their own within a few days. However, if you notice any severe side effects or if the side effects persist, you should contact your veterinarian immediately.

In rare cases, more severe side effects have been reported, such as:

  • Seizures
  • Allergic reactions (such as hives, difficulty breathing, or swelling of the face, tongue, throat, or lips)
  • Blood disorders (such as anemia or clotting problems)

You should seek immediate veterinary attention if you notice any of these signs.

It's also important to note that, as with all medications, some dogs may be more sensitive to Afoxolaner and experience more severe side effects, so it's important to monitor your dog closely after administering the medication and consult with your veterinarian if you have any concerns.

Precautions

When using Afoxolaner, a few precautions should be taken to ensure the safe and effective use of the medication.

  • The first is to follow the product label instructions and consult a veterinarian before administering the medication to your dog. This will ensure that you are using the correct dosage and frequency of administration for your dog's weight and condition.
  • Afoxolaner should not be used in dogs with a known hypersensitivity to the active ingredient or any of the excipients. It's important to tell your veterinarian if your dog has had any previous adverse reactions to parasiticides before administering Afoxolaner.
  • Afoxolaner should not be used in dogs younger than eight weeks of age.
  • Pregnant or lactating females should be treated cautiously, as safety in pregnant and lactating bitches has not been established.
  • As with all medications, it's essential to store Afoxolaner out of reach of children and pets.
  • Care should be taken not to administer the product at a dosage exceeding the recommended one to avoid overdose.
  • It is essential to check with your veterinarian if your dog is on any other medications or supplements, as Afoxolaner may interact with other drugs and cause adverse reactions.

Following these precautions can help ensure that Afoxolaner is used safely and effectively to protect your dog from fleas and ticks.

Signs of toxicity

If you doubt your dog has overdosed with Afoxolaner, please get in touch with your vet immediately. 

Afoxolaner treatment toxicity consists of symptomatic and supportive measures.

Storage

Always store at room temperature (below 30°C/86°F).

Disclaimer

This information is provided for general reference only and is not intended to replace the packaging label or veterinary advice. Always consult your veterinarian to ensure the supplied information applies to your pet. In addition, this page may not include all side effects, uses, brand names, or applications. 

Leave a comment

Please note, comments must be approved before they are published

Best Selling Combo

Best Selling Combo

Heartgard Nexgard Combo for Dogs Flea, Ticks & Heartworm Treatment

Customer Reviews

Overall rating: 4.8 / 5 from 1129 reviews.

Customer photo review of Custom Duty

Fast shipping great quality and price

Custom Duty

Customer photo review of Revolution Plus For Medium Cats 5.6-11 lbs (2.6-5kg)

Two sweet girlies decided to make our deck their home. Mosquitoes are a big problem where we live and we had to get them protected. This was the best bang for the buck. I’ve ordered from 79Pets several times and while delivery is not fast it is very consistent.

Revolution Plus For Medium Cats 5.6-11 lbs (2.6-5kg)

Store owner replied: Thank You Teresa!

Customer photo review of Nexgard Combo For Cats 5.5-16.5 lbs (2.5-7.5 kg)

As a retired veterinary technician I was extremely happy to finally see a flea and heartworm medication that actually does tapeworms too!!!!!!! This is a 1st to my knowledge....I live in a tropical climate where fleas never die so this is heaven sent.

Nexgard Combo For Cats 5.5-16.5 lbs (2.5-7.5 kg)

Store owner replied: Thank You Kimberly.

Customer photo review of Stronghold Teal For Dogs 44-88lbs (20-40kg)

Very happy with the price of Stronghold heart worm med for my dog. Seems to be working well.

Stronghold Teal For Dogs 44-88lbs (20-40kg)

Store owner replied: Thank You Dory!

Customer photo review of Simparica Trio For Dogs 22.1-44 lbs (10-20 kg)

My dog loves this product, never got any issue. Good price , deliver on time. We will definitely keep purchasing with 79 pets.com. Thanks!

Simparica Trio For Dogs 22.1-44 lbs (10-20 kg)

Store owner replied: Thank You Elle!

Customer photo review of NexGard Chew For Small Dogs 10-24lbs (4-10kg)

I have 3 of these little rascals so Michigan flea/tick season can be financially brutal! Thank you for keeping NexGard so affordable.

NexGard Chew For Small Dogs 10-24lbs (4-10kg)

Store owner replied: Thank You Elaine

Customer photo review of Nexgard Combo for Cats 5.5-16.5 lbs (2.5-7.5 kg)

After Seresto collars failed to get rid of fleas, I didn't know where to turn. I saw a post on a page I follow (Kentucky Kitty Cats) saying that they use Nexgard Combo for the cats they shelter. I decided to try it and IT WORKS!

Nexgard Combo for Cats 5.5-16.5 lbs (2.5-7.5 kg)

Store owner replied: Thanks Cari.. We are glad that you found treatment which works for your Cats..

Customer photo review of Revolution Plus For Large Cats 11.1-22lbs (5-10kg)

This is Lexi Marie! She was wondering why mom was so excited for buying flea medicine. I explained to her that we saved $100 and that she would understand some day when she grows up.

Revolution Plus For Large Cats 11.1-22lbs (5-10kg)

Store owner replied: Thanks Tammy!!

Customer photo review of Revolution Plus For Medium Cats 5.6-11 lbs (2.6-5kg)

Last year, I made a visit to the vet. I told them that Kattie/cat had ear mites. They gave me an ointment costing $80canadian. I used it up and purchased another bottle. $160. total not including the cost of the vet visit. No results. The ear mites have been there for a long time. Canadian vets have control of what is sold in Pet stores and you cannot purchase off the shelf products not recognized by them. I jumped at the chance to purchase your produce with a recommended 100% effectivity. I was willing to try, but was suspicions. After a month there was still a little scratching but after 6 weeks, the mites are gone and the scratching is gone. Thank you very much for this mite solution. I recommend it heartily. Harry P.S. Do not tell the Canadian vets as they will outlaw your product.

Revolution Plus For Medium Cats 5.6-11 lbs (2.6-5kg)

Store owner replied: Thanks Harry for review!!

Customer photo review of Revolution Plus For Large Cats 11.1-22lbs (5-10kg)

En fait, c'est le seul produit dont mon chat "Winston" ne soufre pas de problèmes cutané et perte de poils, le "Révolution plus" fait très bien le travail, merci.

Revolution Plus For Large Cats 11.1-22lbs (5-10kg)

Store owner replied: Thanks Alain!