Simparica vs. Comfortis

Comparison between Simparica and Comfortis

Simparica and Comfortis will protect your dogs from fleas, but they are still different, so let's see how they make a difference.

Simparica Chewables and Comfortis tablet control and prevent flea infection, and it needs to administer monthly. They kill existing adult fleas and new adult fleas before they lay eggs and break the breeding cycle.

Simparica also kills ticks like Lone Star ticks, deer ticks, brown dog ticks, and Gulf Coast ticks.

Simparica is only available for dogs, and it is safe at the age of six weeks and minimum body weight of 2.8 lbs (1.3 kg). Simparica should not be given to cats. Comfortis is safe to give to cats at the age of 14 weeks with and minimum weight of 4.1 lbs (1.9 kg) and to dogs at the age of 14 weeks with and minimum body weight of 5 lbs (2.3kg).

Please choose the correct size according to your pet's body weight.

You can use our comparison chart for the most popular flea and tick products.

Simparica For Dogs
Comfortis For Dogs
Kills Fleas
Repels Fleas
Kills Flea Eggs and Larvae
Kills Ticks
Repels Ticks
Kills and/or Repels Mosquitoes
Other Parasites
Safe for Pregnant or Nursing Pets
Consult your veterinarian first
When does it starts working
Kills adult fleas within 3 hours and ticks within 8 hours of administration
Kills fleas in 30 minutes
Liver-flavored chewable
Beef-flavored tablet
Active Ingredient(s)

Shop by Category