How Does NexGard Work?

NexGard chewable tablets are available in four flavors for dogs of different weights. NexGard extinguishes fleas within 8 hours and ticks within 48 hours. After being given, its effects last for at least five weeks against fleas and up to one month against ticks

Nexgard is manufactured by Merial Animal Health which is now part of Boehringer Ingelheim, the same company that manufactures:

So you know this product can be trusted. 

So how do they do it? 

The active substance in NexGard, afoxolaner, is an ectoparasiticide that kills parasites on the skin or the dog's fur, such as fleas, ticks, and mites. Once the flea and ticks start feeding on the dog's blood, the active substance becomes effective.  

Afoxolaner extinguishes parasites by driving an over-stimulation of their nervous system. Afoxolaner blocks the regular activity of charged chloride particles in and out of nerve cells, specifically those associated with gamma-aminobutyric acid. As a result, this substance conveys messages between nerves resulting in uncontrolled movement of the nervous system, paralysis, and death of fleas, ticks, and mites. 

Afoxolaner kills fleas before they lay eggs, which helps contaminate the dog's environment. As a result, these fleas, ticks, and mites rise to the top of the dog's haircoat as they die.

NexGard's active ingredient, afoxolaner, kills fleas and many tick species, which include: 

  • Black-legged ticks
  • American Dog ticks
  • Lone star ticks
  • Brown Dog ticks. 

NexGard is tested and approved for use on pups as young as eight weeks old and doggies over four pounds. The chews are also safe to give to canines presently taking other medicines Nexgard is four for dogs with different weights. In addition, because it is delivered internally, Nexgard is suitable for use on pets that swim and are washed regularly, saving you the fuss of topical medicines. However, Nexgard is not evaluated for use in breeding pets, so you should not give it to pregnant, nursing, or breeding dogs. Instead, discuss Nexgard for dogs with your Vets to provide your dog with intense relief from flea & ticks with monthly tasty chew. 


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